Investigated for its role in the liver due to steatohepatitis (fatty liver) being associated with reduced rates of the one-carbon cycle and subsequent methylation in the liver.
Additionally, ADEMETIONINE appears to be able to normalize levels of glutathione in measured erythrocytes after IV administration and serves to protect the liver from damage
In patients with cirrhosis of the liver ADEMETIONINE daily was able to reduce the rates of liver transplantation or death from cirrhosis from 29% to 12% more benefits was noted in persons with less pathology of cirrhosis compared to late-stage cirrhosis.
